Paul Isaacs' Blog

Autism from the inside

Autism & P53 Gene Deletion – Metabolic Disorders are Apart of Autism “Fruit Salads”

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Dad's 40thOVERVIEW

My Dad was diagnosed with Asperger’s Syndrome in 2010, before that he was diagnosed with a form of blood cancer called CLL, what was also recognised in is that he had a p53 gene deletion which is a protein which protects the body from cancer and other auto-immune attacking virus’/cancers/bacterias.

Some people with Autism is not purely neurological it is biological too and that can mean the metabolic and autoimmune systems can be affected as a result, I believe this broadens the diversity of Autism and its different presentations and also I believe more research should be done in this area. Donna Williams also has these issues within her Autism “Fruit Salad” also.


Over ten years ago in the USA they done a test on 30-40 men on the Autistic Spectrum and they had partial to full p53 deletion.


My Dad is a very positive and empowering man and I wrote a poem which I feel, reflects this I love him dearly. 🙂


In Autism don’t “mourn for the life you could have had” work with what you have got here and now – My Dad has confirmed to me how precious life is, how words should be chosen properly and actions should be thought through – It’s him and what he has been through with a smile, positivity, courage and inspiration. I supported him in hospital with Autism training for the staff on the ward, he supports me when I have no more words and need assistance with things.  Give and take is so important. 

POS ENERGY MAN (inspired by my Father)

Pos- Energy Man came from a land
Where all the bad stuff came and dealt him a hand?
“Oh no” said Pos-Energy man this is not my time, nor my plan
Surrounding himself goodness, surrounding him with love
So he could be a as free as dove
Pos- Energy Man came from a land
But that doesn’t mean he has to play the same tune of the band
Life hasn’t dealt him a bad hand
Because he has a loving plan
To live his life in Pos- Energy Land
That is the Goodness of the Pos- Energy Man

Paul Isaacs 2014


Author: Paul Isaacs

Paul was branded as a “naughty & difficult child” at school. He was classically autistic and non-verbal due to speech articulation difficulties. He had complex sensory issues and appeared both deaf and blind. He gained functional speech around the age of 7 or 8 years old. He went through the mainstream school system with no additional help or recognition of his autism. Consequently, he did not achieve his academic or his social potential and had very low self-esteem. At age 11, Paul was referred to the children’s mental health service with childhood depression where he was regarded as “developmentally underage” and having speech problems. As an adult, Paul had a string of unsuccessful jobs, and his mental health suffered. He developed both Borderline and Schizotypal Personality Disorders in early 2007. He was referred to mental health services and misdiagnosed with “Asperger traits with a complex personality”, which did not satisfy Paul or his family. A local autism organisation put Paul in touch with an experienced psychiatrist, who diagnosed him with Autism at 24 years old. In 2012 Paul was also diagnosed with Scotopic Sensitivity Syndrome by an Irlen Consultant who confirmed that he also had face, object and meaning blindness – conditions which Paul describes eloquently in his speeches and training sessions. He also has dyslexia, dyscalculia and also a dissociative disorder. Having started working as an local autism organisation as a public speaker in 2010, Paul joined their mission to promote autism awareness. His hope is that others will not have to suffer as he did. Now also a core member of our Training Team, Paul continues to enhance true understanding of autism at every opportunity. Paul has released and published 5 books on the subject of autism published by Chipmunka publishing and has contributed to other books too. Having overcome many challenges to achieve the success that he now enjoys, Paul’s message is that Autism is a complex mix of ability and disability. He firmly believes that every Autistic person should have the opportunity to reach their potential and be regarded as a valued member of society. Apart from autism related blogs Paul also write about movies, fashion, art and anything that is of interest. As of August 2015 Paul now works as a freelance speaker, training and consultant in and around the Oxfordshire & Buckinghamshire area. If you are interested please contact him via email at

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